ICON plc
Technical Project Manager - IRT

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ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development.
Technical Project Manager – Interactive Response Technology
We are currently seeking a Technical Project Manager (IRT/RTSM) to join our diverse and dynamic team. As a Technical Project Manager at ICON, you will play a critical role in overseeing the planning, design, execution, and delivery of complex technical solutions that support clinical operations and research initiatives. This includes the implementation and lifecycle management of Interactive Response Technology (IRT/RTSM) systems and their integration with broader clinical trial ecosystems.
You will drive the successful deployment of technology solutions by applying strong project management practices while collaborating with cross functional teams including clinical operations, data management, biostatistics, vendors, and external partners.
What You Will Be Doing
Leading the end-to-end planning, design, and implementation of technical projects, with a strong focus on IRT/RTSM systems supporting clinical trials (e.g., randomization, trial supply management, patient enrollment).
Partnering with clinical and technical stakeholders to define project scope, requirements, and deliverables, ensuring alignment with study protocols and regulatory expectations.
Managing IRT system configuration activities, including user requirements, functional specifications, testing (UAT), and deployment readiness.
Overseeing integrations between IRT and other clinical systems such as EDC, CTMS, ePRO/eCOA, drug supply systems, and data warehouses, ensuring seamless data flow and accuracy.
Coordinating with vendors and third-party providers to support system build, validation, and ongoing maintenance of IRT platforms.
Monitoring project progress, timelines, budgets, and performance metrics; proactively identifying risks, dependencies, and issues, and implementing mitigation plans.
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Ensuring compliance with applicable regulatory standards (e.g., GxP, 21 CFR Part 11) and internal quality processes throughout the project lifecycle.
Facilitating clear and consistent communication between technical teams, clinical stakeholders, and executive leadership to ensure transparency and alignment.
Supporting data reconciliation and integration quality between IRT and downstream systems.
Driving continuous improvement initiatives for IRT delivery processes, standards, and integration frameworks.
Your Profile
Bachelor’s degree in Information Technology, Life Sciences, Project Management, or a related field.
3–5 years of project management experience in a technical environment, preferably within clinical research, pharmaceuticals, or CRO settings.
Proven experience working with IRT/RTSM systems in clinical trials, including system implementation, configuration oversight, and vendor management.
Familiarity with clinical trial system integrations (e.g., IRT–EDC, IRT–CTMS) and data flows across the clinical technology landscape.
Strong understanding of clinical trial processes, including randomization, drug supply management, and patient tracking.
Experience with project management methodologies (Agile, Waterfall, or hybrid) and tools.
Demonstrated ability to manage multiple projects simultaneously with strong organizational, analytical, and problem-solving skills.
Excellent communication and stakeholder management skills, with the ability to translate complex technical concepts to non-technical audiences.
Knowledge of regulatory and compliance requirements in clinical systems (preferred).
What ICON Can Offer You
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.


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In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our Benefits Examples Include
Various annual leave entitlements A range of health insurance offerings to suit you and your family’s needs. Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead. Global Employee Assistance Programme, LifeWorks, offering 24-hour access to a global network of over 80,000 independent specialized professionals who are there to support you and your family’s well-being. Life assurance Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidized travel passes, health assessments, among others.
Visit our careers site to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know or submit a request here
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.
Are you a current ICON Employee? Please click here to apply
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