The University of Manchester
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Two Three-Year Independent Fellowships in Exposome Immunology
Hosted by the MRC Centre of Research Excellence (MRC CoRE) in Exposome Immunology Jointly based at the University of Manchester and the University of Oxford
About the Role
Applications are invited for two three-year independent fellowships within the newly established MRC CoRE in Exposome Immunology, a collaborative initiative between the University of Manchester and the University of Oxford.
The successful candidates will establish their own research groups, leveraging cutting-edge computational approaches, novel experimental models, and/or experimental medicine studies to investigate how pollutants, infections, and genes interact to cause or worsen chronic inflammatory diseases.
These fellowships provide experience-ended postdoctoral researchers the opportunity to develop groundbreaking research ideas and gather preliminary data supporting applications for prestigious career development awards (e.g., Wellcome or MRC funding schemes), ultimately enabling them to launch their own independent research groups at the University of Manchester.
Key Objectives
Applicants must demonstrate a clear vision for developing an original research programme that aligns with the MRC CoRE’s short-term focus, which is to understand immunological mechanisms underlying how environmental exposures contribute to or exacerbate chronic inflammatory diseases of the lung and gut, including:
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- Inflammatory Bowel Disease (IBD)
With a strong emphasis on multidisciplinary science, the ideal candidates will incorporate expertise from disciplines such as:
- Immunology
- Inflammatory disease management
- Atmospheric sciences
- Data science
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Specifically encouraged are projects that bridge traditional silos, including:
- Microbiome responses to environmental exposures and their role in modulating disease.
- Computational biology/bioinformatics integrated with wet-lab research (e.g., genomics, proteomics, metabolomics).
- Mechanistic experimental medicine providing novel scientific insight into disease biology.
- Cross-disciplinary studies involving neuroscience, matrix biology, or genetics within an exposome framework.
Support & Opportunities
Funding & Resources
- 3-year salary package + consumables budget of £20,000 per annum.
- Access to state-of-the-art facilities:
- Gnotobiotic research facilities.
- Spatial multi-omic analysis platforms.
- High-performance computing clusters.
- Controlled pollutant exposure chambers for experimental studies.
- Extensive mentorship to assist in establishing an independent research portfolio.
Academic Environment
- Collaborate with a diverse community—immunologists, data scientists, clinicians, and environmental scientists—working across Oxford and Manchester.
- Join an evolving, vibrant network of exposome immunology experts with shared research goals.
Career Development
- Ideal launchpad for ** 깊이 detached career advancement**, including advising on external grant applications.
Non-Clinical Note
While this role does not cater to clinical applicants, candidates with interest in academic clinical fellowships are encouraged to contact the team for tailoring advice.
Working Arrangements
- The University is supportive of flexible working arrangements and accepts hybrid working models.
- For further information, please visit the University’s flexible working page.
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Benefits
- Outstanding pension scheme (market-leading).
- Comprehensive employee well-being support, including access to an Employee Assistance Programme.
- Enhanced annual leave entitlement, plus additional Christmas closure days.
- Discounts at local and national retailers for staff and dependents.
Payment & Terms
- Appointments are madvise on merit based on qualifications and competency.
- The University subscribes to equal opportunities principles and encourages applications from all backgrounds, including:
- All ages, sexes, and genders/gender identities
- Diverse ethnicities
- Persons with disabilities
- LGBTQ+ communities
- All other protected characteristics under UK laws
Key Contacts
For vacancy enquiries (shortlisting, interviews):
- Judith Allen
- Email: judith.allen@manchester.ac.uk
General enquiries:
- Recruitment Services Team
- Email: recruitmentservices.people@manchester.ac.uk
Technical support:
- Usable link: #Job seeker support tools
Closing Details
- Application due by midnight on Vacancy Closing Date.
- Detailed person specification is available via the Further Particulars document.
Note concerning agencies:
- Applications from Recruitment Agencies are not accepted; inquiries should be emailed to people.talent@manchester.ac.uk.
- Any submission from an agency will be classified as a gift and disregarded due to policy compliance.
All documents and communications will be evaluated in strict adherence to professional disclosure guidelines.
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